During the Roman Liberators' civil war of the 1st Century BC, the Parthians actively supported Brutus and Cassius, invading Syria, and gaining territories in the Levant. It was the first series of conflicts in what would be 719 years of Roman–Persian Wars.Įarly incursions by the Roman Republic against Parthia were repulsed, notably at the Battle of Carrhae (53 BC). The Roman–Parthian Wars (66 BC – 217 AD) were a series of conflicts between the Parthian Empire and the Romans. Antony's Parthian campaign of (40–33 BC).Roman Republic, succeeded by Roman Empire, and client states Romans still maintained their minimal Influence to Armenian Kingdom.(However, despite its nominal allegiance to Rome, it came under direct Parthian leverage.) Kingdom of Osroene which is independent from both sides in Northern Mesopotamia was ceded to the Romans. Parthian Empire gained effective control over Former Roman Client called Armenian Kingdom and Armenian Kingdom became vassal state of Parthian Empire. Southeastern Anatolia, Armenia, South-east Roman frontier ( Osroene, Syria, Mesopotamia) Parthia, shaded yellow, alongside the Seleucid Empire (blue) and the Roman Republic (purple) c.